News and Events

  • New Report on Toxicology in Schools

    October 10, 2016

    Senator Ed Markey of Massachusetts held congressional hearings on the issue of PCBs in schools and then released The ABCs of PCBs: A Toxic Threat to America's Schools-(link is external) in October 2016. It lists key findings and recommendations regarding this vital topic.

  • Researchers Present to EPA

    October 10, 2016

    On September 8, 2016 Drs. Andres Martinez and Keri Hornbuckle of University of Iowa SRP (ISRP) traveled to Boston to meet US EPA Region 1 and Massachusetts Department of Envionmental Protection staff for the first time and share results of initial analyses from the collaborative air quality monitoring project at the New Bedford Harbor Superfund site (NBH). The projects pairs the ISRP, the Boston University Superfund Center, and the Toxics Action Center.

    Funding for the project comes from the NIEHS Superfund Program. Initial results were shared at the meeting and a followup meeting is being arranged for November to share final results. This a great example of collaboration between centers and the affected communities!

  • Superfund Researcher Honored!

    October 10, 2016

    ISRP Project 5 Director Jerry Schnoor was recognized by Environmental Science and Technology in their July 5, 2016 journal.The issue of ES&T was dedicated to honoring Jerry's impacts in areas such as global air issues, groundwater pollutant transport, and remediation, and raising awareness of sustainability on a national and international stage. Congratulations on a very well deserved award!

  • Project 1 in Chemical Research In Toxicology

    October 10, 2016

    ISRP Trainee Gopi Gadupudi, Superfund Director Larry Robertson, and University of Iowa Department of Microbiology Professor Aloysius J. Klingelhutz were published in the August edition of Chemical Research in Toxicology. Their paper was enitled "Diminished Phosphorylation of CREB Is a Key Event in the Dysregulation of Gluconeogenesis and Glycogenolysis in PCB126 Hepatotoxicity."

  • Four Superfund Trainees Successfully Defend their Theses!

    August 10, 2016

    In the spring and summer of 2016 four Iowa Superfund trainees successfully defended their theses. The four are:

    • Aditya Stanam successfully defended on April 20, 2016. His dissertation was entitled “Inflammatory Cytokine Signaling Contribute to Erlotinib Resistance in Head and Neck Cancer”. His Chair and Mentor was Dr. Andrean Simons-Burnett.

     

    • Eric Rodriguez successfully defended on April 21, 2016. His dissertation was entitled "Hydroxylated and   Sulfated Metabolites of Lower Chlorinated PCBs Bind with High Affinity to Human Serum Albumin and Exhibit Selective Toxicity to Neuronal Cells.”  His Chair and Mentor was Dr. Michael Duffel.

     

    • Sabah Hassain Enayah successfully defended her thesis on June 6, 2016. Her dissertation was entitled "Evaluation of the Toxicity Caused by Co-Exposure to Lead (Pb) and Polychlorinated Biphenyls (PCBs)”. Her mentors were Dr. Lars Fuortes and Dr. Gabriele Ludewig.

     

     

    • Gopi Gadupudi successfully defended his thesis on July 11, 2016. His dissertation was entitled “PCB126-induced metabolic disruption: effects on liver metabolism and adipocyte development”mentors were Dr. Larry Robertson and Dr. Aloysius Klingelhutz.
  • Columbus Junction Students Visit!

    July 01, 2016

    On April 21, 2016 twenty- three students from the 7th and 8th grades at Columbus Junction School District visited the labs at the Iowa Superfund Research Program. The students were engaged by the program's inquiry based airborne PCB learning materials. The hands on materials demonstrate the sources, remediation, and human impacts concerning PCBs.

  • Superfund Paper Accepted into Toxicological Sciences Journal!

    July 01, 2016

    Dr. Hans Joachim Lehmler, Iowa Superfund Research Program Analytical Core Leader, had a paper accepted into the prestigious journal Toxicological Sciences. The paper is entitled " 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) decreases hepatic and systemic ratios of epoxide to diol metabolites of unsaturated fatty acids in male rats." The hypothesis tested was PCB 126 exposure alters the levels of oxylipins in rats. The results suggest that oxylipins are potential biomarkers of exposure to PCB 126 and that the P450/sEH pathway is a therapeutic target for PCB 126-mediated hepatotoxicity that warrants further attention.

    Dr. Lehmler collaborated on the project with fellow ISRP researcher Dr. Larry Robertson, Post –Doc fellow Xianai Wu, and three researchers from the University of California-Davis: Jun Wang, Christophe Morisseau, and Bruce Hammock.

     

     

     


  • Duke Superfund Researcher Presents at Iowa Seminar

    July 01, 2016

    Dr. Lee Ferguson from the Duke Superfund Research Program presented at the April 29, 2016 University of Iowa Environmental Science Seminar. His talked was entitled "Helping Contaminants Emerge: New Approaches for Identifying Organic Micropollutants Relevant to Ecological and Human Exposure."

  • Winter Isrp Trainee Graduates

    April 25, 2016

    Winter graduates of the Human Toxicology Program included (pictured to the left) Mao Li, Wen Xin Koh, and Willam Klaren with faculty Gabriele Ludewig, Peter Thorne, and Larry Robertson. Not pictured Dr. Keri Hornbuckle.
    Mao's dissertation was entitled “Protein Adducts and Crosslinking by Reactive Metabolites of Polychlorinated Biphenyls (PCBs).”
    Wen's dissertation was entitled “Polychlorinated Biphenyls and Their Hydroxylated Metabolites in Human Serum from Urban and Rural Cohorts in the United States.”
    William's dissertation was entitled "Assessment of hepatic micronutrients disruption and the hepatotoxicity of 3,3’,4,4’,5-pentachlorobiphenyl (PCB126)."

  • National SOT Meeting ISRP Trainees Gathering

    April 25, 2016

    SOT meeting

    Former trainees of the isrp present at the dinner on Tuesday night (3/15/16) were
    Fabian Grimm (FGrimm@cvm.tamu.edu), now at TAMU,TX;
    Bingxuan Wang (bwang@toxservices.com), now at ToxServices, DC;
    Senthilkumar Perumalkuppusamy (sentilpk@gmail.com), now at NIOSH Cincinnati, OH;
    Van'T Erve, Thomas (NIH/NIEHS) [F] <thomas.van'terve@nih.gov>, now at NIH,NC;
    Jacobus, James A (James.Jacobus@state.mn.us), now at MN state public health, MN;
    Yang Song (songyangwenrong@hotmail.com); now a faculty member in China; he brought 3 of his graduate students to the meeting and to the get-together
    Xin Hu (xin.hu2@emory.edu), now at Emory, GA
    Xie, Wei xiew@RJRT.com, now at RJ Reynolds, NC;

    Current trainees at the get-together were:
    Klaren, William D <william-klaren@uiowa.edu>;
    Gadupudi, Gopi S <gopi-gadupudi@uiowa.edu>;
    Li, Miao <miao-li@uiowa.edu>;
    Enayah, Sabah Hassain Enayah <sabahhassainenayah-enayah@uiowa.edu>;

    Also present were faculty and staff members of the isrp:
    Dodd, Andrea
    Flor, Susanne
    Ludewig, Gabriele
    Robertson, Larry W